ACLS Drugs List with Dosages (2026 Quick Reference Guide)

Introduction

ACLS medications play a critical role in the management of cardiac arrest, bradycardia, and tachycardia. Knowing the correct drugs, indications, and dosages is essential for both ACLS certification exams and real-world clinical practice.

This guide provides a concise, high-yield ACLS drugs list with commonly used doses for quick reference.

Key ACLS Drugs Overview

The most commonly used ACLS medications include:

  • Epinephrine
  • Amiodarone
  • Atropine
  • Adenosine
  • Dopamine
  • Magnesium sulfate

Epinephrine

Indications:

  • Cardiac arrest (VF, pulseless VT, PEA, asystole)
  • Symptomatic bradycardia (infusion)

Dose:

  • Cardiac arrest: 1 mg IV/IO every 3–5 minutes
  • Infusion (bradycardia): 2–10 mcg/min

Key Point: Epinephrine is the first-line drug in cardiac arrest.

Amiodarone

Indications

  • Refractory ventricular fibrillation (VF)
  • Pulseless ventricular tachycardia (VT)

Dose:

  • First dose: 300 mg IV bolus
  • Second dose: 150 mg IV

Key Point: Used after defibrillation attempts fail.

Atropine

Indications

  • Symptomatic bradycardia

Dose:

  • 1 mg IV every 3–5 minutes
  • Maximum: 3 mg

Key Point: First-line medication for bradycardia.

Adenosine

Indications:

  • Stable narrow-complex tachycardia (SVT)

Dose:

  • First dose: 6 mg rapid IV push
  • Second dose: 12 mg if needed

Key Point: Administer rapidly followed by saline flush.

Dopamine

Indications:

  • Symptomatic bradycardia (if atropine ineffective)
  • Hypotension

Dose: 5–20 mcg/kg/min infusion

Magnesium Sulfate

Indications:

  • Torsades de pointes
  • Suspected hypomagnesemia

Dose: 1–2 g IV diluted in fluid

Tips to Remember ACLS Drugs

  • Epinephrine is used in almost all cardiac arrest scenarios
  • Amiodarone is for shock-resistant rhythms
  • Atropine is for bradycardia
  • Adenosine is for SVT
  • Know doses and timing

Final Thoughts

Understanding ACLS medications and their dosages is essential for effective resuscitation. Regular review and practice will help reinforce these critical concepts.

Start ACLS Certification

If you are preparing for ACLS certification, you can complete your course online with flexible learning and instant certificate issuance.

Start your ACLS certification here.

If you are new to life support training, you may also explore our BLS certification course.

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